9-Amino-6-chloro-2-methoxyacridine
(Synonyms:9-氨基-6-氯-2-甲氧基吖啶)
目录号 : KCM13486
CAS No. : 3548-09-2
纯度 : ≥98%
9-Amino-6-chloro-2-methoxyacridine (ACMA) is a cell-permeable fluorescent probe that intercalates into DNA. It selectively binds to poly(dA-dT) sequences with the fluorescence lifetime decreasing with incorporation of guanosine. It is used for labeling DNA and displays excitation/emission spectra of 411/475 nm, respectively. ACMA fluorescence is pH-dependent and is quenched when a pH gradient is established, a property that has been utilized in animal- and plant-based studies. It also inhibits acetylcholinesterase with a Ki value of 49 nM.
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| 分子式 |
C14H11ClN2O
|
| 分子量 |
258.7
|
| CAS号 |
3548-09-2
|
| 中文名称 |
9-氨基-6-氯-2-甲氧基吖啶
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|