| 生物活性 |
7α-hydroxy Dehydroepiandrosterone is a 7α-hydroxylated metabolite of DHEA, catalyzed by intracellular steroid 7α-hydroxylases such as P450 2A1. 7α-Hydroxy-DHEA exhibits biological activity comparable to DHEA but does not convert into compounds with androgenic or estrogenic activity. It induces the activity of thermogenic enzymes such as mitochondrial sn-glycerol-3-phosphate dehydrogenase and cytosolic malic enzyme, enhancing heat production and reducing food utilization efficiency. As a more efficient and safer metabolite compared to DHEA, 7α-Hydroxy-DHEA holds potential for studies in the fields of obesity, metabolic diseases, and adrenal carcinoma. |
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| 分子式 |
C19H28O3
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| 分子量 |
304.42
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| CAS号 |
53-00-9
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| 中文名称 |
7a-羟基去氢表雄酮;7α-羟基去氢表雄酮;7α-羟基脱氢表雄酮标准品;7-羟基-去氢表雄酮
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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纯度： ≥98%
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Data Sheet
