KU-32
目录号 : KG10148 CAS No. : 956498-70-7 纯度 : 98%
KU-32 is a novel, novobiocin-based Hsp90 inhibitor that can protect against neuronal cell death. Treating human islets with KU-32 for 24 hours shows no toxicity. With a minimum of 2-day exposure, KU-32 improves cellular viability by blocking apoptosis. Functionally, isolated human islets release more glucose-stimulated insulin when preincubate in KU-32. KU-32 protects against glucose-induced death of embryonic DRG (dorsal root ganglia) neurons cultured for 3 days in vitro. Diabetic BKS-db/db mice, a model for type 2 diabetes, administered KU-32 for 10 weeks do not show any significant changes in blood glucose and insulin levels, despite having greater insulin staining/beta cell in the pancreas compared to untreated BKS db/db mice.
规格 价格 是否有货 数量
250mg 询价 In-stock

Other Forms of Rapamycin:

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分子式
C20H25NO8
分子量
407.41
CAS号
956498-70-7
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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