PHY34
目录号 : KG10357
CAS No. : 2130033-55-3
纯度 : 98%
PHY34 is an inhibitor of late-stage autophagy.It is cytotoxic to OVCAR-3 and OVCAR-8 ovarian cancer cells (IC50 = 4 nM for both) and induces apoptosis in the same cells when used at a concentration of 100 nM. PHY34 increases the number of LC3B puncta and induces autophagosome accumulation in HeLa cells (EC50s = 1.99 and 3.86 nM, respectively). It reduces tumor growth in an OVCAR-8 mouse xenograft model when administered at a dose of 0.75 mg/kg.
Other Forms of Rapamycin:
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| 分子式 |
C30H30O12
|
| 分子量 |
582.6
|
| CAS号 |
2130033-55-3
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|