SS28
目录号 : KG10378
CAS No. : 141172-08-9
纯度 : 98%
SS28, a SRT501 analog with oral bioavailability, inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase. SS28 results in apoptosis rather than necrosis tubulin. Tubulin.
SS28 (0-20 μM) induces cytotoxicity in different cancer cell lines.SS28 treatment (5 μM for A549 and 2 μM for CEM) results in cell cycle arrest at G2/M phase leading to apoptosis upon further incubation. Cell Proliferation Assay Cell Line: CEM, Reh, Nalm6, SUDHL8, Molt4, A549, HeLa 293T cells.
SS28 (15 mg/kg. b.wt.) treatment results in inhibition of tumor cell proliferation. Animal Model: BALB/c mice using EAC cells.
Other Forms of Rapamycin:
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| 分子式 |
C18H20O3
|
| 分子量 |
284.35
|
| CAS号 |
141172-08-9
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|