NMS-P515
目录号 : KG10468
CAS No. : 1262395-13-0
纯度 : 98%
NMS-P515 is a potent, orally active and stereospecific PARP-1 inhibitor, with a Kd of 16 nM and an IC50 of 27 nM (in Hela cells). Anti-tumor activity. PARP-1|16 nM (Kd)|PARP-1|27 nM (IC50, in Hela cells)
NMS-P515 (80 mg/kg, orally daily for 12 days) exhibits potent antitumor activity in mouse models based pancreatic cancer. Animal Model: Subcutaneously implanted Capan-1 pancreatic (BRCA2-mutated) mouse xenografts.
Other Forms of Rapamycin:
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| 分子式 |
C21H29N3O2
|
| 分子量 |
355.47
|
| CAS号 |
1262395-13-0
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|