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PF 06651600 malonate
目录号 : KG10471 CAS No. : 2140301-97-7 纯度 : 98%
Data Sheet 产品使用指南
Potent and selective JAK3 inhibitor (IC50 = 33.1 μM). Exhibits no significant activity against a panel of other kinases including JAK1, JAK2 and TYK2. Inhibits phosphorylation of STAT5, induced by IL-2, IL-4, IL-7 and IL-15. Suppresses Th1 and Th17 T-cell differentiation and function in vitro. Reduces paw swelling in a rat model of arthritis and reduces disease severity in a rat EAE model.
规格 价格 是否有货 数量
5mg
In-stock
25mg
In-stock
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分子式
C15H19N5O.C3H4O4
分子量
389.41
CAS号
2140301-97-7
中文名称
PF 06651600 malonate - Bio-X
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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