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SIRT-IN-1 (Synonyms:4-[4-[2-[(2,2-二甲基-1-氧代丙基)氨基]乙基]-1-哌啶基]-噻吩并[3,2-d]嘧啶-6-羧酰胺)
目录号 : KG10485 CAS No. : 1431411-60-7 纯度 : 98%
Data Sheet 产品使用指南
SIRT-IN-1 is a potent inhibitor of SIRT1/2/3, with IC50s of 15, 10, 33 μM, respectively. SIRT-IN-1 (compound 28) is one of the most potent truncated pan SIRT1/ 2/3 inhibitor, the IC50 values are 0.015, 0.010, 0.033 μM, respectively. SIRT-IN-1 (SIRT1/2/3 pan inhibitor) binds identically in the catalytic active site (RMS=0.29 ?), occupying the nicotinamide C-pocket and acetyl lysine substrate channel.
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250mg 询价 In-stock
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分子式
C19H27N5O2S
分子量
389.52
CAS号
1431411-60-7
中文名称
4-[4-[2-[(2,2-dimethyl-1-oxopropyl)amino]ethyl]-1-piperidinyl]-Thieno[3,2-d]pyrimidine-6-carboxamide
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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