NPD-1335
目录号 : KG10624
CAS No. : 2376326-31-5
纯度 : 98%
NPD1335 is a Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death. pKi: 6.9 (TbrPDEB1); pIC50: 6.2 (T. brucei) (NPD-1335)
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| 分子式 |
C28H29N3O3
|
| 分子量 |
455.55
|
| CAS号 |
2376326-31-5
|
| 中文名称 |
NPD-1335
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|