Mutated EGFR-IN-2
目录号 : KG10817
CAS No. : 2050906-97-1
纯度 : 98%
Mutated EGFR-IN-2 (compound 91) is a mutant-selective EGFR inhibitor extracted from patent WO2017036263A1, which potently inhibits single-mutant EGFR (T790M) and double-mutant EGFR (including L858R/T790M (IC50=<1nM) and ex19del/T790M), and can suppress activity of single gain-of-function mutant EGFR (including L858R and ex19del) as well. Mutated EGFR-IN-2 shows anti-tumor antivity. EGFRT790M EGFRL858R EGFRex19del EGFR (L858R/T790M)|<1 nM (IC50)|EGFR (ex19del/T790M)
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| 分子式 |
C29H35FN8O3
|
| 分子量 |
562.64
|
| CAS号 |
2050906-97-1
|
| 中文名称 |
Mutated EGFR-IN-2
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|