PF-07104091
目录号 : KG10913
CAS No. : 2460249-19-6
纯度 : 98%
PF-07104091 is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2).
PF-07104091 (Example 13) inhibits CDK1/cyclin A2, CDK4/cyclin D1, CDK6/cyclin D3 and CDK9, with Kis of 110, 238, 465 and 117 nM, respectively.
Other Forms of Rapamycin:
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| 分子式 |
C19H28N6O4
|
| 分子量 |
404.46
|
| CAS号 |
2460249-19-6
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|