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Nefazodone-d6 (hydrochloride)
目录号 : KG11214 CAS No. : 1330236-06-0 纯度 : 98%
Data Sheet 产品使用指南
Nefazodone-d6 (hydrochloride) is intended for use as an internal standard for the quantification of nefazodone by GC- or LC-MS. Nefazodone is a serotonin (5-HT), norepinephrine, and dopamine reuptake inhibitor (SNDRI; Kis = 137, 570, 2,380 nM, respectively, in rat brain synaptosomes). It is also an antagonist of 5-HT2A, 5-HT1A, and histamine H1 receptors, as well as α1- and α2-adrenergic receptors (α2-ARs; Kis = 7.1, 52, 30, 5.5, and 84 nM, respectively). Nefazodone (100 mg/kg) reduces immobility time in the tail suspension test in gerbils. However, it is toxic to isolated human hepatocytes in a cultured sandwich hepatocyte preparation when used at a concentration of 30 µM. Formulations containing nefazodone have previously been used in the treatment of depression.
规格 价格 是否有货 数量
500 µg
In-stock
1mg
In-stock
5mg
In-stock
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分子式
C25H26ClD6N5O2.HCl
分子量
512.5
CAS号
1330236-06-0
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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