ST4206
目录号 : KG11926
CAS No. : 1246018-36-9
纯度 : 98%
ST4206 is a potent adenosine A2A antagonist, with Kis of 12 nM and 197 nM for adenosine A2A receptor and adenosine A1 receptor, respectively.
ST4206 inhibits agonist-induced cAMP accumulation with an IC50 of 990 nM.
ST4206 (10, 20, and 40 mg/kg, p.o.) antagonizes haloperidol-induced catalepsy, and increases motor activity in a dose dependent manner in mice. ST4206 (20 and 40 mg/kg) significantly increases the number of contralateral turns induced by l-DOPA in rats. ST4206 is orally active at concentrations of 10, 20, and 40 mg/kg in haloperidol-induced catalepsy in mice.
Other Forms of Rapamycin:
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| 分子式 |
C12H14N8O
|
| 分子量 |
286.29
|
| CAS号 |
1246018-36-9
|
| 中文名称 |
2-Butanone, 4-[6-amino-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-2-yl]-
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|