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DHMEQ racemate (rel-DHMEQ) (Synonyms:顺式(+/-)-2-羟基-n-(2-羟基-5-氧代-7-噁双环[4.1.0]-3-庚烯-3-基)苯甲酰胺;DHMEQ (racemate))
目录号 : KG12204 CAS No. : 287194-38-1 纯度 : 98%
Data Sheet 产品使用指南
DHMEQ racemate is a NF-κB inhibitor. DHMEQ racemate is less active than (-)-DHMEQ. DHMEQ racemate (DHM3EQ) and (-)-DHMEQ (DHM2EQ) inhibits TNF-a-induced NF-kB activation. (-)-DHMEQ is more potent and less toxic than DHMEQ racemate. The antiarthritic effects of (-)-DHMEQ (DHM2EQ) and DHMEQ racemate (DHM3EQ) are examined on type-II collagen-induced arthritis in DBA1/J mice. This animal model is widely used for evaluation of antirheumatic drugs because of its pathological similarities to human rheumatoid arthritis. The arthritis is elicited and scored. (-)-DHMEQ markedly inhibits type-II-collagen-induced arthritis in mice, whereas DHMEQ racemate tends to only slightly inhibit it.
规格 价格 是否有货 数量
2mg
In-stock
5mg
In-stock
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分子式
C13H11NO5
分子量
261.23
CAS号
287194-38-1
中文名称
顺式(+/-)-2-羟基-n-(2-羟基-5-氧代-7-噁双环[4.1.0]-3-庚烯-3-基)苯甲酰胺
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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