PF 9601N (Synonyms:5-苄氧基-N-2-丙炔-1-基-1H-吲哚-2-甲胺)
目录号 : KG12521 CAS No. : 133845-63-3 纯度 : 98%
PF 9601N is an inhibitor of monoamine oxidase B (MAO-B). It selectively inhibits MAO-B in mouse brain homogenates ex vivo (ID50 = 381 nmol/kg) and prevents MPTP-induced reductions in dopamine levels in the striatum of 8- to 9-week-old mice when administered at doses ranging from 29.5 to 8.47 µmol/kg. PF 9601N (0.027 µmol/kg) prevents MPTP-induced lesions in 9- to 10-month-old mice. It also increases the duration of contralateral rotational behavior induced by L-DOPA in a rat model of Parkinson’s disease induced by 6-OHDA when administered at doses of 40 and 60 mg/kg.
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5mg
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10mg
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25mg
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50mg
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分子式
C19H18N2O
分子量
290.4
CAS号
133845-63-3
中文名称
PF 9601N
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2