ADHP - CAS:119171-73-2 - KKL Med Inc.

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ADHP (Synonyms:10-Acetyl-3,7-dihydroxyphenoxazine)

目录号 : KM9259 CAS No. : 119171-73-2 纯度 : 98%

Data Sheet SDS 产品使用指南

ADHP 是一种荧光过氧化物酶底物（λ_ex=530 nm, λ_em=590 nm）。

规格	价格	是否有货	数量
1mg		In-stock
5mg		In-stock
10mg		In-stock
25mg		In-stock
50mg		In-stock
100mg		In-stock
10 mM * 1 mL in DMSO		In-stock

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生物活性

ADHP is a fluorogenic peroxidase substrate (λ_ex=530 nm, λ_em=590 nm).

体外研究

To obtain the parameters K_m and k_cat for Compound I, two independent methods are used. Initially, the oxidation of ADHP using the injector functionality built-in to the fluorescence plate reader is studied. The auto-injector dispenses the H₂O₂ to initiate the reaction, as a means of generating a set of progress curves. Analysis for MPO-mediated oxidation of ADHP gives a K_m of 31±4 μM and the k_cat of 186± 6 s.The k_obs also increases over the experimental range of ADHP concentrations from 1 to 80 μM and for the converse experiment holding substrate constant over 3 to 45 nM MPO. The apparent second order rate constant obtain from the slope of k_obs against ADHP concentration K_on is 2.1±0.2 mM/s.

分子式

C₁₄H₁₁NO₄

分子量

257.24

CAS号

119171-73-2

中文名称

10-乙酰基-3,7-二羟基吩嗪

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

2-8°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

DMSO: 116.67 mg/mL (453.55 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.8874 mL	19.4371 mL	38.8742 mL
5 mM	0.7775 mL	3.8874 mL	7.7748 mL
10 mM	0.3887 mL	1.9437 mL	3.8874 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： 98%