Anatabine
(Synonyms:(S)-(-)-新烟草碱;(2S,4R)-4-[[(4-甲基苯基)磺酰基]氧基]-1,2-吡咯烷二甲酸 1-叔丁酯;(S)-安那他品;(S)-新烟草碱;新烟草碱)
目录号 : KE3637
CAS No. : 581-49-7
纯度 : ≥95%
Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheimer's disease effects, it inhibits BACE-1 transcription and reduces BACE-1 protein levels in human neuronal like SHSY-5Y cells suggesting that the Aβ lowering properties of anatabine are mediated via a regulation of BACE-1 expression.
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| 生物活性 |
Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via an inhibition of STAT3 phosphorylation.Anatabine has anti-Alzheimer's disease effects, it inhibits BACE-1 transcription and reduces BACE-1 protein levels in human neuronal like SHSY-5Y cells suggesting that the Aβ lowering properties of anatabine are mediated via a regulation of BACE-1 expression.
|
| 分子式 |
C10H12N2
|
| 分子量 |
160.22
|
| CAS号 |
581-49-7
|
| 中文名称 |
(S)-新烟草碱
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|