CD73-IN-14
目录号 : KM34934 CAS No. : 2407356-67-4
CD73-IN-14 是一种有效、选择性和具有口服活性的 CD73 抑制剂,IC50 值为 0.17 nM。CD73-IN-14 增加肿瘤浸润性 CD8+ 细胞数量并显示出抗肿瘤活性。CD73-IN-14 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。
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生物活性
D73-IN-14 is a potent, selective and orally active CD73 inhibitor with an IC50 value of 0.17 nM. CD73-IN-14 increases the number of tumor-infiltrating CD8+ cells and shows anti-tumor activity. CD73-IN-14 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
分子式
C26H26ClN7O9
分子量
615.98
CAS号
2407356-67-4
中文名称
CD73-IN-14
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2