3′-Azido-2′,3′-dideoxy-GTP (Synonyms:(AZddGTP))
目录号 : KM35226 CAS No. : 94059-38-8
3′-Azido-2′,3′-dideoxy-GTP (AZddGTP) 是一种选择性端粒酶抑制剂,Ki 值为 1.5 μM。3′-Azido-2′,3′-dideoxy-GTP 能被端粒酶整合到 DNA 3′ 末端。3′-Azido-2′,3′-dideoxy-GTP 在体外可抑制 HeLa 细胞端粒酶活性。
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生物活性
3′-Azido-2′,3′-dideoxy-GTP (AZddGTP) is a selective telomerase inhibitor with a Ki value of 1.5 μM. 3′-Azido-2′,3′-dideoxy-GTP can be incorporated into the 3′-terminus of DNA by telomerase. 3′-Azido-2′,3′-dideoxy-GTP inhibits telomerase activity in HeLa cells in vitro.
分子式
C10H15N8O12P3
分子量
532.19
CAS号
94059-38-8
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2