| 生物活性 |
GBR-401 is a humanized anti-CD19 monoclonal antibody with high affinity for FcγRIIIa. GBR-401 exerts a potent in vitro and in vivo cytotoxic activity against various B-cell malignancies. GBR-401 induces cell death by antibody dependent cellular cytotoxicity (ADCC) and direct killing effect. GBR-401 demonstrates potent activity of depleting malignant B cells and prolongs mice survival in multiple xenograft severe combined immunodeficiency (SCID) mice models.
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| CAS号 |
1931954-95-8
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
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400-881-9290
Data Sheet
