| 生物活性 |
Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice.
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| 分子量 |
183.48 kDa
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| CAS号 |
2254522-19-3
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| 中文名称 |
Modakafusp alfa
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| 运输条件 |
Shipping with dry ice.
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| 储存方式 |
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纯度： 96%
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Data Sheet
