Romiplostim 是一种 TPO (thrombopoietin protein) 的 Fc 肽融合蛋白模拟物，同时也是 c-Mpl 激动剂。Romiplostim 可与 c-Mpl 结合，刺激巨核细胞介导的血小板生成，激活与内源性 TPO 相同的下游信号通路。Romiplostim 可用于造血急性辐射综合征、慢性免疫性血小板减少症的相关研究。
| 生物活性 |
Romiplostim is a fusion protein analogue of TPO (thrombopoietin protein) Fc peptide, and is a peptide-body molecule. Romiplostim increases platelet production by activating the thrombopoietin receptor TPO receptor. The peptidosome molecule has two identical single-stranded subunits, each consisting of 269 amino acid residues.
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|---|---|
| 分子式 |
59 kDa
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| CAS号 |
267639-76-9
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| 中文名称 |
罗米司亭
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| 运输条件 |
Shipping with dry ice.
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| 储存方式 |
Store at -80°C for 2 years. Aliquots should be stored at the same temperature after first use to avoid multiple freeze-thaws. |
纯度： ≥99%
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Data Sheet
