| 生物活性 |
Telisotuzumab (ABT-700) (powder) is a bivalent humanized IgG1 anti-c-Met monoclonal antibody. Telisotuzumab (powder) binds cellular c-Met and disrupts its productive dimerization and activation induced by HGF or by the high density of c-Met on the cell surface independent of ligand. Telisotuzumab (powder) induces apoptosis. Telisotuzumab (powder) can be used for the study of cancers harboring amplified MET, such as gastric and lung cancers.
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| 分子量 |
146.1 kDa
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| CAS号 |
1781223-80-0
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| 中文名称 |
Telisotuzumab
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
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