CGKRK是一种通过噬菌体展示技术发现的肿瘤归巢肽。它以能量和硫酸肝素受体依赖的方式介导细胞内化。定位于细胞中的线粒体，CGKRK肽对新生血管内皮细胞和肿瘤组织表现出选择性的高结合亲和力，但对非致瘤细胞没有。
| 生物活性 |
CGKRK is a tumor homing peptide, discovered by phage display technique. It mediates the cellular internalization in energy and heparin sulfate receptor-dependent manner. Then it localizes to mitochondria in cells. CGKRK peptide exhibited selective high binding affinity to the neovascular endothelial cells and tumor tissues, but not to the non-tumorigenic cells. |
|---|---|
| 分子式 |
C23H46N10O6S
|
| 分子量 |
590.74
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
-20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
纯度： 95%
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Data Sheet
