3-Acetyl-7-Hydroxycoumarin 是一种高选择性 17- β-羟基类固醇脱氢酶 1 型 (17β-HSD1) 抑制剂，对 17β-HSD1 的抑制作用在 6 μM 下达到 57%。3-Acetyl-7-Hydroxycoumarin 有望用于乳腺癌、子宫内膜异位症等激素依赖性疾病的研究。
| 生物活性 |
3-Acetyl-7-Hydroxycoumarin is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17β-HSD1 at 6 μM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis. |
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| 分子式 |
C11H8O4
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| 分子量 |
204.18
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| CAS号 |
10441-27-7
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| 中文名称 |
3-乙酰基-7-羟基-苯并吡喃-2-酮
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
2-8°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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| 溶解性数据 |
In Vitro:
DMSO: ≥ 100 mg/mL (489.76 mM) * "≥" means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
纯度： 95%
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Data Sheet
