Urotensin I - CAS:83930-33-0

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Urotensin I (Synonyms:Catostomus urotensin I)

目录号 : KM13826 CAS No. : 83930-33-0 纯度 : 98%

Data Sheet 产品使用指南

Urotensin I (Catostomus urotensin I) 是一种类 CRF 样肽，可作为CRF 受体激动剂，在细胞实验中，对人 CRF₁，CRF₂ 和大鼠 CRF_2α 受体的 pEC₅₀ 值分别为 11.46，9.36 和 9.85，对 hCRF₁，rCRF_2α 和 mCRF_2β 受体的 K_i 值分别为 0.4，1.8 和 5.7 nM。

规格	价格	是否有货	数量
500µg		In-stock
1mg		In-stock
5mg		In-stock

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Other Forms of Rapamycin:

Cortagine In-stock
Urocortin, human In-stock
Urotensin I In-stock

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生物活性	Urotensin I (Catostomus urotensin I), a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC₅₀s of 11.46, 9.36 and 9.85 for human CRF₁, human CRF₂ and rat CRF_2α receptors in CHO cells, and K_is of 0.4, 1.8, and 5.7 nM for hCRF₁, rCRF_2α and mCRF_2β receptors, respectively.
体外研究	Urotensin I is 2-3 times more potent than CRF or sauvagine in stimulating ACTH release from a superfused goldfish anterior pituitary cell column. Rat tail artery strips were incubated in the presence of 4 x 10(-3) M theophylline and Urotensin I (UI). At the concentrations of 1.50, 7.50 mU/ml but not of 0.75 mU/ml Urotensin I, the content of cAMP increased significantly.
体内研究	Intraperitoneal injections of urotensin I, a CRF-like neuropeptide isolated from the caudal neurosecretory system of the teleost Catostomus commersoni, ovine CRF and sauvagine all produced significant increases in circulating levels of plasma cortisol in goldfish in which endogenous ACTH secretion was suppressed with betamethasone.
分子式	C₂₁₀H₃₄₀N₆₂O₆₇S₂
分子量	4869.46
CAS号	83930-33-0
中文名称	硬骨鱼紧张肽I
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.