Adrenomedullin (AM) (22-52), human - CAS:159899-65-7

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Adrenomedullin (AM) (22-52), human (Synonyms:22-52-Adrenomedullin (human))

目录号 : KM17857 CAS No. : 159899-65-7 纯度 : 98%

Data Sheet 产品使用指南

Adrenomedullin (AM) (22-52), human，NH₂ 末端截短的 adrenomedullin 类似物，为肾上腺髓质素 (adrenomedullin receptor) 受体拮抗剂，同时在猫后肢血管床中，对降钙素基因相关肽 (CGRP) 受体也具有拮抗作用。

规格	价格	是否有货
500µg		In-stock
1mg		In-stock
5mg		In-stock
10mg	询价	In-stock
50mg	询价	In-stock

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Other Forms of Rapamycin:

Adrenomedullin (AM) (22-52), human In-stock
Rat CGRP-(8-37) In-stock
MK-3207 In-stock

KKL Med 的所有产品和服务仅用于科学研究，不能被用于人体，兽医，我们也不向个人提供产品和服务。

生物活性

Adrenomedullin (AM) (22-52), human, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat.

体外研究

Adrenomedullin (AM) (22-52), human shows no effect on hindlimb perfusion pressure responses to adrenomedullin (ADM) at 120 nmol. However, Adrenomedullin (AM) (22-52), human selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) at 30 nmol, with similar effect to that of CGRP antagonist.
Adrenomedullin (AM) (22-52), human competitively inhibits the binding of the Adrenomedullin in a dose-dependent manner, inhibits Adrenomedullin -induced cAMP accumulation in rat vascular smooth muscle cells.

分子式

C₁₅₉H₂₅₂N₄₆O₄₈

分子量

3575.98

CAS号

159899-65-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 100 mg/mL (27.96 mM; Need ultrasonic)

H2O : 50 mg/mL (13.98 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.2796 mL	1.3982 mL	2.7964 mL
5 mM	0.0559 mL	0.2796 mL	0.559 mL
10 mM	0.0280 mL	0.1398 mL	0.2796 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： 98%