Gly-Pro-pNA (hydrochloride) - CAS:103213-34-9

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Gly-Pro-pNA (hydrochloride) (Synonyms:N-甘氨酰脯氨酰-对硝基苯胺盐酸盐;甘氨酰脯氨酸对硝基苯胺;甘氨酰-脯氨酰-对硝基苯胺盐酸盐)

目录号 : KCM10121 CAS No. : 103213-34-9 纯度 : ≥98%

Data Sheet 产品使用指南

Gly-Pro-pNA is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm. DPP IV inactivates the two peptides responsible for a majority of nutrient-stimulated insulin secretion: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1). This substrate can be used to screen for DPP IV inhibitors, which have emerged as a new class of experimental antidiabetic agents.

规格	价格	是否有货	数量
10mg		In-stock
25mg		In-stock
50mg		In-stock
100mg		In-stock

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生物活性

Gly-Pro-pNA (hydrochloride) is a chromogenic peptide substrate that can be cleaved by the circulating enzyme dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA (hydrochloride) is mainly used to detect the activity of aminopeptidases such as DPP IV. Gly-Pro-pNA (hydrochloride) can be investigated as an experimental antidiabetic agent.

体外研究

Gly-Pro-pNA (hydrochloride) is mainly used to detect the activity of aminopeptidases such as DPP IV.

分子式

C₁₃H₁₆N₄O₄^.HCl

分子量

328.76

CAS号

103213-34-9

中文名称

N-甘氨酰脯氨酰-对硝基苯胺盐酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据

In Vitro:

DMSO: 100 mg/mL (304.17 mM; Need ultrasonic)

H2O : 50 mg/mL (152.09 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.0417 mL	15.2087 mL	30.4173 mL
5 mM	0.6083 mL	3.0417 mL	6.0835 mL
10 mM	0.3042 mL	1.5209 mL	3.0417 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： ≥98%