Ivabradine-d3 (hydrochloride) - CAS:1217809-61-4

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Ivabradine-d3 (hydrochloride) (Synonyms:盐酸伊伐布雷定 D3)

目录号 : KCM10694 CAS No. : 1217809-61-4 纯度 : 98%

Data Sheet SDS 产品使用指南

Ivabradine-d is intended for use as an internal standard for the quantification of ivabradine by GC- or LC-MS. Ivabradine is a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker that blocks the mixed sodium/potassium inward funny current (I) in HEK293 cells expressing mouse HCN1, human HCN2, and human HCN4 (ECs = 4.5, 4.52, and 4.28 μM, respectively). In vivo, ivabradine (10 mg/kg per day) reduces heart rate, incidence of ventricular tachycardia and ventricular fibrillation, and arrhythmic mortality in a rat model of myocardial infarction. Formulations containing ivabradine have been used in the treatment of heart failure and angina.

规格	价格	是否有货	数量
500μg		In-stock
1mg		In-stock

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生物活性

Ivabradine-d3 (hydrochloride) is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent.

分子式

C₂₇H₃₃D₃N₂O₅^.HCl

分子量

508.06

CAS号

1217809-61-4

中文名称

盐酸伊伐布雷定 D3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： 98%

Data Sheet

SDS

产品使用指南

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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Other Forms of Rapamycin:

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