17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid - CAS:1233715-33-7

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17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

目录号 : KCM10761 CAS No. : 1233715-33-7 纯度 : ≥95%

Data Sheet 产品使用指南

Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 µM).

规格	价格	是否有货	数量
100μg		In-stock
250μg		In-stock
500μg		In-stock
1mg		In-stock

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生物活性	17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid (17-Oxo-DPA; 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA) is an electrophilic oxo-derivative (EFOX) of the docosahexaenoic acid (DHA) (HY-B2167). 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is generated during inflammation by COX-2-catalyzed mechanism in activated macrophages. 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid acts as an agonist for PPARγ and a modulator for NF-κB signaling pathway, inhibits the production of pro-inflammatory cytokines and nitric oxide, and exhibits anti-inflammatory efficacy.
分子式	C₂₂H₃₂O₃
分子量	344.5
CAS号	1233715-33-7
中文名称	17-keto-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid Exclusive
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-80°C