CAY10647 (Synonyms:Anti-melanoma agent 3)
目录号 : KCM10838 CAS No. : 1253697-49-2 纯度 : ≥98%
CAY10647 is an aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg). This compound also binds to tubulin (K = 3.4 μM) and prevents tubulin polymerization.
规格 价格 是否有货 数量
1mg
In-stock
5mg
In-stock
10mg
In-stock

Other Forms of Rapamycin:

KKL Med 的所有产品和服务仅用于科学研究,不能被用于人体,兽医,我们也不向个人提供产品和服务。
生物活性

CAY10647 is a 2-aryl-4-benzoyl-imidazole (ABI) derivative and an inhibitor of melanoma xenogeneic tumors. CAY10647 exerts anticancer activity by interacting with the colchicine binding site to inhibit tubulin polymerization.

体外研究

CAY10647 has anti proliferative activity and can inhibit the growth of melanoma and prostate cancer cell lines.

体内研究

CAY10647 (10, 30 mg/kg; ip; once a day for 14 days) can significantly inhibit tumor growth in B16-F1 tumor bearing mice.

分子式
C17H13FN2O2
分子量
296.3
CAS号
1253697-49-2
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2