CAY10649 (Synonyms:5-LOX-IN-7;(Z)-2-(4-氯苯基)-5-(4-甲氧基亚苄基)-5H-噻唑-4-酮)
目录号 : KCM10897 CAS No. : 1272519-89-7 纯度 : ≥98%
5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction. CAY10649 is a thiazolinone compound that demonstrates direct inhibition of 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) (IC = 0.28 μM) and a soluble fraction of a S100 PMNL cell lysate (IC = 0.09 μM) after stimulation with calcium and arachidonic acid.
规格 价格 是否有货 数量
1mg
In-stock
5mg
In-stock
10mg
In-stock

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生物活性

CAY10649 is a potent LOX inhibitor. CAY10649 has the potential for the research of inflammatory and allergic diseases and certain cancer.

分子式
C17H12ClNO2S
分子量
329.8
CAS号
1272519-89-7
中文名称
(Z)-2-(4-氯苯基)-5-(4-甲氧基亚苄基)-5H-噻唑-4-酮
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2