5(S),6(R)-11-trans DiHETE - CAS:129263-59-8

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5(S),6(R)-11-trans DiHETE

目录号 : KCM10946 CAS No. : 129263-59-8 纯度 : ≥95%

Data Sheet 产品使用指南

5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor. 5(S),6(R)-11-trans DiHETE has been found in rat kidney homogenates and is potentially formed by the epoxide hydrolase pathway in this tissue. The isomerase activity responsible for the conversion of leukotriene B (LTB) to 6-trans LTB in rat kidney homogenates has also been implicated in its formation. 5(S),6(R)-11-trans DiHETE is not a substrate for soybean lipoxygenase. The biological activity of 5(S),6(R)-11-trans DiHETE has not been reported.

规格	价格	是否有货	数量
25μg		In-stock
50μg		In-stock
100μg		In-stock

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生物活性	(5S,6R)-DiHETEs is the isomer of (5S,6R)-DiHETE. (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC50 of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists.
分子式	C₂₀H₃₂O₄
分子量	336.5
CAS号	129263-59-8
中文名称	(5S,6R,7E,9E,11E,14Z)-5,6-Dihydroxy-7,9,11,14-icosatetraenoic aci d
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-80°C