3-Aminopropylphosphonic Acid - CAS:13138-33-5

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3-Aminopropylphosphonic Acid (Synonyms:3-氨基丙烷-1-磷酸)

目录号 : KCM11006 CAS No. : 13138-33-5 纯度 : ≥95%

Data Sheet SDS 产品使用指南

3-Aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABA receptors (IC = 1.5 μM in a radioligand binding assay). It induces relaxation in unstimulated isolated guinea pig ileum longitudinal muscle and reverses GABA- and baclofen-induced inhibition of twitch responses in isolated guinea pig ileum longitudinal muscle. 3-APPA (5 mg/kg) completely inhibits GABA- and baclofen-induced inhibition of vagally stimulated bronchospasms in guinea pigs. It also reverses the antitussive effect of baclofen in cats when administered at a dose of 3 mg/kg.

规格	价格	是否有货	数量
25mg		In-stock
50mg		In-stock
100mg		In-stock
250mg		In-stock
500mg		In-stock
1g		In-stock
10 mM * 1 mL in Water		In-stock

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生物活性

3-Aminopropylphosphonic Acid is a phosphonic acid analogue of GABA and a GABAB receptor agonist.

体外研究

3-Aminopropylphosphonic acid (0.1-100 μM) inhibited the binding of 3H-baclofen (a radiolabeled GABAB receptor agonist) in rat meninges, with an IC50 of 1.5 μM.

3-Aminopropylphosphonic acid can be used for grafting modification of mesoporous titanium dioxide powder, and its amino functional groups can affect surface interactions and coordination modes.

分子式

C₃H₁₀NO₃P

分子量

139.09

CAS号

13138-33-5

中文名称

3-氨基丙烷-1-磷酸;(3-氨基丙基)磷酸;3-氨基丙烷磷酸;3-氨基丙基磷酸;3-氨基丙烷-1-磷酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

2-8°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

H2O : 100 mg/mL (718.96 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	7.1896 mL	35.9479 mL	71.8959 mL
5 mM	1.4379 mL	7.1896 mL	14.3792 mL
10 mM	0.7190 mL	13.5948 mL	7.1896 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： ≥95%