bpV(pic) (potassium hydrate) - CAS:148556-27-8

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bpV(pic) (potassium hydrate) (Synonyms:bpV(pic) (potassium hydrate))

目录号 : KCM11535 CAS No. : 148556-27-8 纯度 : ≥96%

Data Sheet 产品使用指南

bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC = 31 nM). It also inhibits the vascular endothelial PTP, PTP-β (IC = 12.7 μM), and PTP-1βB (IC = 61 μM). bpV(pic) is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells, stimulating lipogenesis in adipocytes, and inhibiting the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors of rat liver endosomes.

规格	价格	是否有货	数量
5mg		In-stock
25mg		In-stock

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生物活性	bpV(pic) (potassium hydrate) is a PTEN inhibitor with IC₅₀ 31 nM. BpV(pic) potassium hydrate is also an insulin simulator that activates insulin receptor kinase in cultured liver cancer cells, stimulates adipogenesis in adipocytes, and inhibits the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors in rat hepatosomes.
分子式	C₆H₄NO₇V^.₂K[₂H₂O]
分子量	367.3
CAS号	148556-27-8
中文名称	bpV(pic) (potassium hydrate)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)