Cyclo(L-Leu-L-Trp) - CAS:15136-34-2

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Cyclo(L-Leu-L-Trp) (Synonyms:Cyclo(L-leucyl-L-tryptophyl))

目录号 : KCM11598 CAS No. : 15136-34-2 纯度 : ≥95%

Data Sheet 产品使用指南

Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite originally isolated from Penicillium. It is active against various bacteria (MICs = 125-1000 µg/ml) and fungi (MICs = 8-64 µg/ml), and it inhibits the production rate of hydroxy radicals in an electron spin resonance (ESR) spectroscopy-based assay (IC = 1.8 µM). Cyclo(L-Leu-L-Trp) is a bitter tastant that can rapidly permeate rat taste cell membranes ex vivo when used at a concentration of 1 mM. It also acts as a melatonin receptor agonist in X. laevis melanophores, inhibiting cAMP accumulation when used at a concentration of 20 µM, an effect that is blocked by the melatonin receptor antagonist luzindole .

规格	价格	是否有货	数量
5mg		In-stock
25mg		In-stock

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生物活性

Cyclo(L-Leu-L-Trp) is a cyclic dipeptide that inhibits a various of bacteria and fungi. Cyclo(L-Leu-L-Trp) is a melatonin receptor agonist and is also used as a bitter ligand.

分子式

C₁₇H₂₁N₃O₂

分子量

299.37

CAS号

15136-34-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, Sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (Sealed storage, away from moisture)

溶解性数据

In Vitro:

DMSO: ≥ 100 mg/mL (334.03 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.3403 mL	16.7017 mL	33.4035 mL
5 mM	0.6681 mL	3.3403 mL	6.6807 mL
10 mM	0.3340 mL	1.6702 mL	3.3403 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： ≥95%