Ras Inhibitory Peptide - CAS:159088-48-9

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Ras Inhibitory Peptide

目录号 : KCM11749 CAS No. : 159088-48-9 纯度 : ≥95%

Data Sheet 产品使用指南

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.

规格	价格	是否有货	数量
500μg		In-stock
1mg		In-stock
5mg		In-stock
10mg		In-stock

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生物活性

Ras Inhibitory Peptide is a Ras inhibitor with antitumor activity.

体外研究

Ras Inhibitory Peptide (5 μM) inhibits HUVEC migration and abolishes the preventive effect of 30 μM farnesyl alcohol (FOH) on the migration inhibition of HUVEC mediated by 60 μM terbinafine.

分子式

C₅₃H₉₁N₁₉O₁₁

分子量

1170.4

CAS号

159088-48-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： ≥95%

Data Sheet

产品使用指南

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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Other Forms of Rapamycin:

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