Bizine - CAS:1591932-50-1

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Bizine

目录号 : KCM11751 CAS No. : 1591932-50-1 纯度 : ≥95%

Data Sheet 产品使用指南

Bizine is a phenelzine analog that inhibits lysine-specific demethylase 1 (LSD1; K = 59 nM). It is 23-fold, 63-fold, and >100-fold selective for LSD-1 over monoamine oxidase (MAO) A, MAOB, and LSD2, respectively. Bizine has been shown to induce bulk histone H3 lysine 4 dimethylation in LNCaP cancer cells (EC = ~2 µM) and, at 0.5 µM, to protect neurons exposed to oxidative stress.

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1mg		In-stock
5mg		In-stock
10mg		In-stock

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生物活性

Bizine, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine can modulate bulk histone methylation in cancer cells. Bizine shows neuroprotective effects.

分子式

C₁₈H₂₃N₃O

分子量

297.39

CAS号

1591932-50-1

中文名称

Bizine Dihydrochloride

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： ≥95%

Data Sheet

产品使用指南

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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