TCS-OX2-29 - CAS:1610882-30-8

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TCS-OX2-29 (Synonyms:TCS-OX2-29 HCl;TCS-OX2-29 hydrochloride;OX2R antagonist)

目录号 : KCM11775 CAS No. : 1610882-30-8 纯度 : ≥95%

Data Sheet 产品使用指南

Orexin receptors R1 (OX1R) and OX2R mediate the action of the neuropeptides orexin A and orexin B. TCX-OX2-29 is an antagonist of OX2R (pK = 7.5) that exhibits >250-fold selectivity for hOX2R compared with hOX1R (ICs = 40 nM and >10,000 nM, respectively). It blocks the inhibitory action of orexin A on forskolin-induced cAMP formation.

规格	价格	是否有货	数量
5mg		In-stock
10mg		In-stock
50mg		In-stock

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Other Forms of Rapamycin:

Daridorexant hydrochloride In-stock
DORA-22 In-stock
TCS-OX2-29 In-stock
Seltorexant hydrochloride In-stock

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生物活性

TCS-OX2-29 (hydrochloride) is a potent, high affinities and selective orexin-2 receptor (OX2R) antagonist with an IC₅₀ value of 40 nM and a pKI value of 7.5. TCS-OX₂-29 displays ~250-fold selectivity for OX₂ over OX1.

分子式

C₂₃H₃₁N₃O₃^.HCl

分子量

433.97

CAS号

1610882-30-8

中文名称

TCS-OX 2-29

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： ≥95%

Data Sheet

产品使用指南

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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Other Forms of Rapamycin:

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