OAC3 - CAS:182564-41-6 - KKL Med Inc.

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OAC3 (Synonyms:N-(4-氟苯甲酰基)-5-氨基-1H-吲哚;Oct4 inducer-1)

目录号 : KCM12119 CAS No. : 182564-41-6 纯度 : ≥98%

Data Sheet SDS 产品使用指南

Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells. OAC3 is an Oct4-activating compound which activates expression through the Oct4 gene promoter. In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC3 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells from embryonic fibroblasts.

规格	价格	是否有货	数量
5mg		In-stock
10mg		In-stock
25mg		In-stock
50mg		In-stock
10 mM * 1 mL in DMSO		In-stock

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OAC3 In-stock

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生物活性

OAC3 is a potent Oct4 activator. OAC3 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. OAC3 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time.

体外研究

OAC3 (1 μM) enhances reprogramming efficiency by activating Oct4-luc reporter and Nanog-luc reporter in embryonic stem cells (ESCs). OAC3 increases induced pluripotent stem cells (iPSC) generation and accelerates the appearance of iPSC-like colonies. OAC3 (1 μM; 4F (OSKM) infected mouse embryonic fibroblast (MEF)) enhances reprogramming efficiency in iSF1 media.

分子式

C₁₅H₁₁FN₂O

分子量

254.26

CAS号

182564-41-6

中文名称

N-(4-氟苯甲酰基)-5-氨基-1H-吲哚

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

2-8°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

DMSO: 250 mg/mL (983.25 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.9330 mL	19.6649 mL	39.3298 mL
5 mM	0.7866 mL	3.9330 mL	7.8660 mL
10 mM	0.3933 mL	1.9665 mL	3.9330 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： ≥98%