19,20-Epoxycytochalasin C (Synonyms:19,20-环氧细胞松弛素C)
目录号 : KCM12232 CAS No. : 189351-79-9 纯度 : ≥95%
19,20-Epoxycytochalasin C is a fungal metabolite originally isolated from Nemania sp. UM10M. It inhibits the growth of chloroquine-sensitive and -resistant strains of P. falciparum (ICs = 0.07 and 0.05 ng/ml, respectively) without inducing cytotoxicity in Vero cells (IC = >4,760 ng/ml). 19,20-Epoxycytochalasin C is also phytotoxic, reducing growth of lettuce and bentgrass plants when used at a concentration of 1 mg/ml.
规格 价格 是否有货 数量
1mg
In-stock
5mg 询价 In-stock

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生物活性

19,20-Epoxycytochalasin C , a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity.

体外研究

19,20-Epoxycytochalasin C shows moderate toxicity to cell line SK-MEL with an IC50 of 8.02 µM.

体内研究

Evaluation of in vivo antimalarial activity of 19,20-Epoxycytochalasin C in a mouse model at 100 mg/kg dose shows that this compound has weak suppressive antiplasmodial activity and is toxic to animals.

分子式
C30H37NO7
分子量
523.62
CAS号
189351-79-9
中文名称
19,20-环氧细胞松弛素C
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2