CAY10719
目录号 : KCM12294 CAS No. : 1942919-63-2 纯度 : ≥98%
CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC = 0.23 µM) with little activity at ABCG1. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and to inhibit ATPase activity.
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1mg
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5mg
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10mg
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25mg
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生物活性

CAY10719 is a selective inhibitor for breast cancer resistance protein (ABCG2), with an IC50 of 0.238 µM. CAY10719 reverses the ABCG2-mediated resistance toward SN-38 and inhibit the ATPase activity.

体外研究

CAY10719 exhibits cytotoxicity towards MDCK II BCRP and MDCK wild-type cells, with CI50s of 5.82 and 6.55 μM, respectively.
CAY10719 inhibits ATPase with an IC50 of 0.038 μM.

分子式
C25H20Cl2N2O2
分子量
451.34
CAS号
1942919-63-2
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2