N-acetyl-D-Leucine - CAS:19764-30-8

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N-acetyl-D-Leucine (Synonyms:N-乙酰-D-亮氨酸;N-Acetyl-R-leucine)

目录号 : KCM12332 CAS No. : 19764-30-8 纯度 : ≥95%

Data Sheet SDS 产品使用指南

N-acetyl-D-Leucine is a derivative of D-leucine and a substrate for various enzymes in the amidohydrolase superfamily. It has been used to characterize the function of amidohydrolase enzymes from B. bronchiseptica, S. coelicolor, and G. oxydans.

规格	价格	是否有货	数量
100g		In-stock
500g		In-stock
10 mM * 1 mL in DMSO		In-stock

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Other Forms of Rapamycin:

AZD0095 In-stock
MCT1-IN-3 In-stock
N-acetyl-D-Leucine In-stock
MCT1-IN-2 In-stock
7ACC1 In-stock

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生物活性

N-acetyl-D-Leucine is an amino-protecting group N-substituted chiral amino acid. N-acetyl-D-Leucine is a PepT1 and MCT1 inhibitor with IC50 of 0.74 and 11 mM, respectively. N-acetyl-D-Leucine can be used for LysoTracker signaling studies.

体外研究

N-acetyl-D-Leucine is not a substrate of LAT1 and PepT1, but rather an inhibitor of PepT1 with an IC50 of 0.74 mM.
N-acetyl-D-Leucine is a substrate of MCT1 with a Km of 1.0 mM and also an inhibitor of MCT1, with an IC50 of 11 mM.
N-acetyl-D-Leucine (1-5 mM; 7 days) did not show a significant dose-dependent effect on LysoTracker signals in NPC1-deficient Chinese hamster ovary cells, but a statistically significant effect was observed at higher concentrations (5 mM).

体内研究

N-acetyl-D-Leucine (24 mg per rat; intravenous injection; once daily) had no significant effect on the compensation and postural imbalance scores of nystagmus in rats.

分子式

C₈H₁₅NO₃

分子量

173.21

CAS号

19764-30-8

中文名称

N-乙酰-D-亮氨酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO: 100 mg/mL (577.33 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	5.7733 mL	28.8667 mL	57.7334 mL
5 mM	1.1547 mL	5.7733 mL	11.5467 mL
10 mM	0.5773 mL	2.8867 mL	5.7733 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： ≥95%

Data Sheet

SDS

产品使用指南

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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Other Forms of Rapamycin:

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