13(S)-HpODE - CAS:33964-75-9

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13(S)-HpODE (Synonyms:13(S)-过氧羟基-(9Z,11E,15Z)-十八碳三烯酸)

目录号 : KCM13383 CAS No. : 33964-75-9 纯度 : ≥95%

Data Sheet 产品使用指南

13(S)-HpODE is produced by the oxidation of linoleic acid by lipoxygenase-1 (LO-1) in many plants including soybean, flaxseed, apples, and tea leaves, and by 15-LO in mammals. In plants, 13(S)-HpODE is the preferred substrate for the garlic bulb divinyl ether synthase. In mammalian tissues, 13(S)-HpODE is generally reduced to 13(S)-HODE , a compound which exhibits many biological activities. A direct action for 13(S)-HpODE has been demonstrated in Syrian hamster embryo cells where it stimulates EGF-dependent mitogenesis and up-regulation of EGF-dependent tyrosine phosphorylation. Membrane-esterified 13(S)-HpODE has been identified in human atherosclerotic plaques.

规格	价格	是否有货	数量
50μg		In-stock
100μg		In-stock

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生物活性	13(S)-HpODE is a linoleic acid metabolite found in several plants and mammals.
体外研究	13(S)-HPODE can be produced by the oxidation of linoleic acid by lipoxygenase-1 in many plants. The dioxygenation catalyzed by a 15-lipoxygenase and a reduction of intermediate 13-HPODE by a glutathione-dependent peroxidase can form 13(S)-HODE. 13(S)-HPODE can stimulate EGF-dependent mitogenesis and up-regulation of EGF-dependent tyrosine phosphorylation by inhibiting the dephosphorylation of the EGFR.
分子式	C₁₈H₃₂O₄
分子量	312.4
CAS号	33964-75-9
中文名称	13(S)-过氧羟基-(9Z,11E,15Z)-十八碳三烯酸
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-80°C