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2-Amino-3-methylimidazo[4,5-f]quinoline (Synonyms:2-氨基-3-甲基-3H-咪唑并喹啉)
目录号 : KCM15153 CAS No. : 76180-96-6 纯度 : ≥98%
Data Sheet 产品使用指南
2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) is a food-derived carcinogen that is found in high temperature-cooked meats and tobacco smoke. In humans, IQ is metabolized by the cytochrome (CYP) P450 isoform CYP1A2 and conjugated by N-acetyltransferase or sulfotransferase to a metabolite that reacts with DNA to form adducts. It induces formation of single-base substitutions and exon deletions and increases cell death in vitro in a concentration-dependent manner. In vivo, IQ increases the incidence of squamous cell hyperplasias in the stomach of p53 knockout mice and increases hepatocellular lesions in female mice regardless of p53 status.
规格 价格 是否有货 数量
10mg
In-stock
50mg
In-stock
100mg
In-stock
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Other Forms of Rapamycin:

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生物活性

2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine is a mutagenic compound.
分子式
C11H10N4
分子量
198.22
CAS号
76180-96-6
中文名称
2-氨基-3-甲基-3H-咪唑并喹啉
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据
In Vitro: 

DMSO: 10 mg/mL (50.45 mM; ultrasonic and warming and heat to 60°C)

配制储备液
                                           
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
                                                                                                                    
1 mM 5.0449 mL 25.2245 mL 50.4490 mL
5 mM 1.0090 mL 5.0449 mL 10.0898 mL
10 mM 0.5045 mL 2.5224 mL 5.0449 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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