D-Fructose 1-phosphate disodium - CAS:71662-09-4

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D-Fructose 1-phosphate disodium (Synonyms:D-果糖-1-磷酸二钠盐)

目录号 : KM32375 CAS No. : 71662-09-4

Data Sheet 产品使用指南

D-Fructose 1-phosphate disodium 是果糖代谢途径中的关键中间代谢物。D-Fructose 1-phosphate disodium 是连接果糖代谢与葡萄糖代谢调控的关健信号分子，其作用方式是作为变构调节剂，抵消葡萄糖激酶- 调节蛋白复合物的抑制作用，从而在底物水平上精细调控肝脏的糖代谢方向。

规格	价格	是否有货	数量
1mg		In-stock

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Other Forms of Rapamycin:

cis-9-Tetradecenal In-stock
D-Fructose 1-phosphate disodium In-stock
Calcium stearate In-stock
1-Hydroxyoctadecane-d2 In-stock
Glycerol-d3 In-stock

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生物活性	D-Fructose 1-phosphate disodium is a key intermediate metabolite in the fructose metabolic pathway. As a key signaling molecule linking fructose metabolism and glucose metabolic regulation, D-Fructose 1-phosphate disodium acts as an allosteric modulator to counteract the inhibitory effect of the glucokinase-regulatory protein complex, thereby finely regulating the direction of hepatic glucose metabolism at the substrate level.
体外研究	D-Fructose 1-phosphate disc can stimulate the activity of glucokinase in isolated liver cells, with a semi maximal effective dose of 30 pmol/mg protein; Pancreatic glucagon can weaken the stimulating effect. D-Fructose 1-phosphate disc (1 mM) is a specific substrate for Clostridium difficile fructose-1-phosphate kinase, with a Km value of 160 μM, and is inhibited by sulfate and phosphate ions. D-Fructose 1-phosphate disc can directly dissociate the large liver GKRP-GK complex, relieving GKRP mediated GCK inhibition. D-Fructose 1-phosphate disodium can inhibit PKM2 in intestinal epithelial cells, thereby driving HIF-1 α activation, hypoxic cell survival, elongation, and enhanced nutrient absorption.
分子式	C₆H₁₁Na₂O₉P
分子量	304.10
CAS号	71662-09-4
中文名称	D-果糖-1-磷酸二钠盐
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)