ARN14988
目录号 : KCM11573
CAS No. : 1502027-70-4
纯度 : ≥98%
ARN14988 is a potent inhibitor of acid ceramidase (IC = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells (ECs = 41.8 and 67.7 µM, respectively).
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| 分子式 |
C16H24ClN3O5
|
| 分子量 |
373.83168
|
| CAS号 |
1502027-70-4
|
| 中文名称 |
5-chloro-3-[(hexylamino)carbonyl]-3,6-dihydro-2,6-dioxo-1(2H)-pyrimidinecarboxylicacid,2-methylpropylester
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|