4-Epianhydrochlortetracycline (hydrochloride) (Synonyms:4-差向四环素盐酸盐)
目录号 : KCM11730 CAS No. : 158018-53-2 纯度 : >95%
4-Epianhydrochlortetracycline is a derivative of tetracycline . It inhibits matrix metalloproteinase-9 (MMP-9) activity in a dose-dependent manner in an assay for collagen degradation. 4-Epianhydrochlortetracycline also completely inhibits neutrophil-derived MMP-9 degradation of denatured collagen at a concentration of 500 μg/ml. Unlike tetracycline, 4-epianhydrochlortetracycline lacks antibiotic activity.
规格 价格 是否有货 数量
1mg
In-stock
5mg
In-stock

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生物活性

4-Epianhydrochlortetracycline (hydrochloride) is an inhibitor of matrix metalloproteinases (MMPs), particularly gelatinase B (Gelatinase B, EC 3.4.24.35), with inhibition rates of 100% at 500 μg/mL, 70% at 125 μg/mL, and 40% at 31 μg/mL. 4-Epianhydrochlortetracycline (hydrochloride) is promising for research in chronic inflammatory diseases.

分子式
C22H21ClN2O7.HCl
分子量
497.33
CAS号
158018-53-2
中文名称
4-差向四环素盐酸盐
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2