Tasimelteon-d5 - CAS:1962124-51-1

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Tasimelteon-d5 (Synonyms:BMS-214778-d5; VEC-162-d5)

目录号 : KCM12316 CAS No. : 1962124-51-1 纯度 : 98%

Data Sheet 产品使用指南

Tasimelteon-d is intended for use as an internal standard for the quantification of tasimelteon by GC- or LC-MS. Tasimelteon is a melatonin (MT) receptor agonist. It selectively binds MT and MT receptors (Ks = 0.304 and 0.069 nM, respectively, in NIH3T3 cells expressing the recombinant human receptors) over a panel of 160 additional receptors and enzymes at 10 µM. Tasimelteon inhibits forskolin-induced cAMP accumulation with EC values of 0.79 and 1 nM in NIH3T3 cells expressing the MT or MT receptor, respectively. Formulations containing tasimelteon have been used in the treatment of non-24-hour sleep-wake disorder.

规格	价格	是否有货	数量
1mg		In-stock
5mg		In-stock

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Other Forms of Rapamycin:

Tasimelteon-d5 In-stock
Cyclo(L-Leu-L-Trp) In-stock
Melatonin In-stock

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生物活性

Tasimelteon-d5 is the deuterium labeled Tasimelteon. Tasimelteon is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24).

分子式

C₁₅H₁₄D₅NO₂

分子量

250.35

CAS号

1962124-51-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： 98%

Data Sheet

产品使用指南

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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Other Forms of Rapamycin:

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The molarity calculator equation

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