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Sodium chloride, for cell culture is an orally active salt. Sodium chloride, for cell culture induces the expression of ATP1A1. Sodium chloride, for cell culture induces the pro-inflammatory cytokines IL-2, TNFα, IL-9 and several chemokines. Sodium chloride, for cell culture enhances the anti-tumor activities of Digoxin against small cell lung cancer. Sodium chloride, for cell culture drives autoimmune disease by the induction of pathogenic Th17 cells.

Sodium chloride (10-70 mM; 72 h) can enhance the anti-tumor activity of Digoxin in small cell lung cancer cell lines.
Sodium chloride (40 mM) can specifically promote the generation of highly pathogenic Th17 cells.

Sodium chloride (3%; oral and intravenous injection; Administration of Digoxin via drinking water and intravenous injection of 200 μ L of 3% NaCl 6 hours prior to treatment can enhance the anti-tumor activity of Digoxin in a mouse model of small cell lung cancer.
Sodium chloride (1% -4%; oral; Feed containing 4% NaCl and drinking water containing 1% NaCl can induce Th17 cells and exacerbate experimental autoimmune encephalomyelitis in mice.

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